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For years it has been demonstrated that parasitic helminths have a coexistence with mammalian hosts whereby they survive for several years in known hostile conditions of their hosts. Many explanations exist describing how these parasitic helminths are able to survive. Recently a lot of studies have focused on the antioxidant systems now shown to exist in these parasites and which may serve as defence tactics against the host-generated oxygen radicals. This review tries to compile what is known to date of the enzymatic antioxidant systems in selected parasitic helminths.