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Acta Parasitologica, Vol.46, No. 4, 2001, 233-241
Bruschi Fabrizio, Lucchi Naomi W. - Enzymatic antioxidant systems in helminth parasites: no doubt on their evasive role.

Department of Experimental Pathology, Medical Biotechnology, Infectious Diseases and Epidemiology, Faculty of Medicine and Surgery, University of Pisa, Via Roma 55, 56126 Pisa, Italy

For years it has been demonstrated that parasitic helminths have a coexistence with mammalian hosts whereby they survive for several years in known hostile conditions of their hosts. Many explanations exist describing how these parasitic helminths are able to survive. Recently a lot of studies have focused on the antioxidant systems now shown to exist in these parasites and which may serve as defence tactics against the host-generated oxygen radicals. This review tries to compile what is known to date of the enzymatic antioxidant systems in selected parasitic helminths.

KEY WORDS: Helminths, antioxidant enzymes, SOD, catalase, glutathione peroxidase, glutathione S-transferase, peroxidoxins
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