Volume 50/Number 1/Abstract 2
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Acta Parasitologica, Vol.50, No. 1, 2005, 19-24
Katarzyna Donskow, Anna Bajer, Malgorzata Bednarska and Edward Sinski* - Experimental transmission of Cryptosporidium parvum isolates from wild rodents and calves to laboratory bred common voles (Microtus arvalis)

Department of Parasitology, Institute of Zoology, Faculty of Biology, Warsaw University, 1 Miecznikowa Street, 02-096 Warsaw, Poland
*Corresponding author: esinski@biol.uw.edu.pl

The oocysts of Cryptosporidium parvum isolated from Microtus arvalis, Clethrionomys glareolus and calves were used in laboratory experiments carried out on 35 M. arvalis. Oocysts were detected in 43% of 14 voles infected with C. parvum derived from calves and in 54% of 13 voles infected with C. parvum isolates from C. glareolus. All voles inoculated with oocysts from M. arvalis (MA-voles) developed infection. There were observed differences in courses of infection between the three groups of voles with MA-voles demonstrating the most typical curve with an acute phase of infection in the first 4 weeks and a 2-weeklong phase of self-curing. The infections with 'heterologous' C. parvum isolates (C. glareolus and calf isolates) transformed into chronic infections with lower oocyst productions. A strong host age effect was observed on prevalence of C. parvum among voles of different ages. Eight-month-old voles did not become infected and in older animals the infections were milder. The successful cross-transmission of two C. parvum isolates to M. arvalis suggests that this species should be considered as reservoir host for this important parasite of humans and animals.

KEY WORDS: Calves, cross-transmission, Cryptosporidium parvum, infectivity, isolates, Microtus arvalis, oocyst output

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